| Index | Irene | South Dakota | National |
| Average Test Scores | 55% | 48% | 48% |
| Student/Teacher ratio | n/a | 14:1 | 16:1 |
| Total public schools | n/a | 340 | 79,221 |
| Total private schools | n/a | 76 | 24,874 |
| Total post-secondary schools | n/a | 25 | 7,963 |
| Index | Irene | South Dakota | National |
| Completed 8th grade | 92.9% | 89.1% | 84.3% |
| Completed high school | 88.0% | 86.8% | 83.0% |
| Completed some college | 51.5% | 60.4% | 59.4% |
| Completed associate degree | 27.9% | 38.5% | 38.5% |
| Completed bachelors | 17.5% | 27.5% | 30.3% |
| Completed masters | 5.5% | 8.1% | 11.5% |
| Completed professional degree | 2.1% | 2.5% | 3.3% |
| Completed doctorate | 0.3% | 1.2% | 1.3% |
There are a total of n/a public schools, n/a private schools and n/a post-secondary schools in Irene. Using the proficiency score averages, the average test scores for Irene, SD schools is 55%. The average student to teacher ratio is n/a. In Irene, SD, an average of 92.9% of students have completed 8th grade and an average of 88.0% have completed high school.
| City | Population | Avg. Test Scores | National Avg. |
| Yankton, SD | 14,619 | 53% | 10.9% |
| Centerville, SD | 952 | 52% | 8.7% |
| Viborg, SD | 793 | 50% | 4.2% |
| Wakonda, SD | 267 | 45% | 7.3% |
| Gayville, SD | 374 | 35% | 27.8% |
| Irene, SD | 549 | 55% | 14.6% |
| City | Population | Avg. Test Scores | National Avg. |
| Leslie, AR | 549 | 60% | 24.0% |
| Andover, OH | 549 | 62% | 28.8% |
| St. Leonard, MD | 549 | 35% | 28.1% |
| Terry, MT | 549 | 45% | 6.3% |
| Hulbert, OK | 549 | 23% | 51.9% |
| Irene, SD | 549 | 55% | 14.6% |
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