| Index | Mayesville | South Carolina | National |
| Average Test Scores | 27% | 47% | 48% |
| Student/Teacher ratio | n/a | 16:1 | 16:1 |
| Total public schools | n/a | 932 | 79,221 |
| Total private schools | n/a | 369 | 24,874 |
| Total post-secondary schools | n/a | 96 | 7,963 |
| Index | Mayesville | South Carolina | National |
| Completed 8th grade | 78.8% | 83.0% | 84.3% |
| Completed high school | 76.4% | 81.6% | 83.0% |
| Completed some college | 44.8% | 56.6% | 59.4% |
| Completed associate degree | 26.4% | 35.6% | 38.5% |
| Completed bachelors | 20.4% | 26.5% | 30.3% |
| Completed masters | 6.2% | 9.6% | 11.5% |
| Completed professional degree | 1.0% | 2.5% | 3.3% |
| Completed doctorate | 0.0% | 1.1% | 1.3% |
There are a total of n/a public schools, n/a private schools and n/a post-secondary schools in Mayesville. Using the proficiency score averages, the average test scores for Mayesville, SC schools is 27%. The average student to teacher ratio is n/a. In Mayesville, SC, an average of 78.8% of students have completed 8th grade and an average of 76.4% have completed high school.
| City | Population | Avg. Test Scores | National Avg. |
| Lamar, SC | 1,123 | 49% | 2.4% |
| Turbeville, SC | 990 | 45% | 6.3% |
| Dalzell, SC | 3,086 | 41% | 15.6% |
| Sumter, SC | 39,758 | 32% | 34.1% |
| Mayesville, SC | 674 | 27% | 43.8% |
| City | Population | Avg. Test Scores | National Avg. |
| Elwood, NE | 674 | 53% | 9.4% |
| Liberal, MO | 674 | 31% | 34.7% |
| Brandon, MN | 674 | 64% | 33.3% |
| Alpha, IL | 674 | 27% | 43.8% |
| Calhoun, TN | 674 | 46% | 5.2% |
| Mayesville, SC | 674 | 27% | 43.8% |
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