| Month | Temp. (min) | Temp. (max) | Temp. (avg) | Precipitation |
| January | 31°F | 52°F | 41°F | 8.3" |
| February | 33°F | 56°F | 44°F | 5.5" |
| March | 41°F | 65°F | 52°F | 4.6" |
| April | 49°F | 74°F | 61°F | 11.8" |
| May | 57°F | 80°F | 68°F | 10.6" |
| June | 66°F | 87°F | 76°F | 5.9" |
| July | 68°F | 89°F | 77°F | 6.8" |
| August | 67°F | 87°F | 76°F | 6.1" |
| September | 61°F | 81°F | 71°F | 11.6" |
| October | 49°F | 72°F | 60°F | 8.6" |
| November | 39°F | 63°F | 50°F | 11.0" |
| December | 36°F | 56°F | 45°F | 12.8" |
| Index | Mayo | South Carolina | National |
| Air quality index | 44 | 37 | 42 |
| Pollution index | 7,804,180 | 3,620,438 | 2,726,193 |
| Measurement | Total |
| Days measured | 357 |
| Days with good air quality | 249 |
| Days with moderate air quality | 106 |
| Days w/ poor A.Q. for sensitive groups | 2 |
| Days with unhealthy air quality | 0 |
| Pollutant | Total |
| Arsenic | 0.010% |
| Benzene | 0.070% |
| Carbon Tetrachloride | 0.020% |
| Lead | 0.050% |
| Mercury | 0.003% |
| City | Population | Air Quality Index | National Avg. |
| Gaffney, SC | 12,733 | 36 | 28.0% |
| Caroleen, NC | 447 | 36 | 28.0% |
| Cliffside, NC | 707 | 36 | 28.0% |
| Henrietta, NC | 455 | 36 | 28.0% |
| Chesnee, SC | 597 | 36 | 28.0% |
| Mayo, SC | 1,770 | 44 | 12.0% |
| City | Population | Air Quality Index | National Avg. |
| Fort Deposit, AL | 1,770 | 52 | 4.0% |
| Stamps, AR | 1,770 | 39 | 22.0% |
| Scotland Neck, NC | 1,770 | 36 | 28.0% |
| Columbia City, OR | 1,770 | 18 | 64.0% |
| Rogue River, OR | 1,770 | 26 | 48.0% |
| Mayo, SC | 1,770 | 44 | 12.0% |
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