| Month | Temp. (min) | Temp. (max) | Temp. (avg) | Precipitation |
| January | 20°F | 37°F | 28°F | 2.1" |
| February | 21°F | 38°F | 29°F | 2.0" |
| March | 34°F | 54°F | 43°F | 3.0" |
| April | 44°F | 66°F | 55°F | 4.3" |
| May | 54°F | 74°F | 63°F | 3.7" |
| June | 64°F | 84°F | 74°F | 6.0" |
| July | 66°F | 86°F | 76°F | 4.5" |
| August | 66°F | 86°F | 75°F | 4.2" |
| September | 57°F | 79°F | 67°F | 4.3" |
| October | 45°F | 64°F | 54°F | 3.9" |
| November | 36°F | 54°F | 44°F | 2.7" |
| December | 23°F | 38°F | 29°F | 2.4" |
| Index | Center | Missouri | National |
| Air quality index | 41 | 97 | 42 |
| Pollution index | 964,937 | 1,630,255 | 2,726,193 |
| Measurement | Total |
| Days measured | 241 |
| Days with good air quality | 208 |
| Days with moderate air quality | 33 |
| Days w/ poor A.Q. for sensitive groups | 0 |
| Days with unhealthy air quality | 0 |
| Pollutant | Total |
| Arsenic | 0.003% |
| Benzene | 0.010% |
| Carbon Tetrachloride | 0.002% |
| Lead | 0.130% |
| Mercury | 0.120% |
| City | Population | Air Quality Index | National Avg. |
| Frankford, MO | 452 | 41 | 18.0% |
| Perry, MO | 760 | 41 | 18.0% |
| Florida, MO | 0 | 41 | 18.0% |
| Curryville, MO | 248 | 41 | 18.0% |
| Monroe City, MO | 2,810 | 41 | 18.0% |
| Center, MO | 467 | 41 | 18.0% |
| City | Population | Air Quality Index | National Avg. |
| Lisman, AL | 467 | 36 | 28.0% |
| Paragon, IN | 467 | 42 | 16.0% |
| Kenvir, KY | 467 | 39 | 22.0% |
| Simpson, LA | 467 | 30 | 40.0% |
| Soudan, MN | 467 | 35 | 30.0% |
| Center, MO | 467 | 41 | 18.0% |
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