| Statistic | De Witt | Missouri | National |
| Population | 78 | 6,137,428 | 328,239,523 |
| Population density (sq mi) | 323 | 90 | 91 |
| Median age | 57.9 | 38.3 | 37.7 |
| Male/Female ratio | 0.9:1 | 1.0:1 | 1.0:1 |
| Married (15yrs & older) | 82% | 57% | 55% |
| Families w/ Kids under 18 | 27% | 42% | 43% |
| Speak English | 96% | 94% | 79% |
| Speak Spanish | 4% | 3% | 13% |
| Race | De Witt | Missouri | National |
| White | 79.49% | 82.53% | 73.35% |
| Black | 12.82% | 11.58% | 12.63% |
| Asian | 0.00% | 1.78% | 5.22% |
| American Indian | 0.00% | 0.42% | 0.82% |
| Native Hawaiian | 0.00% | 0.11% | 0.18% |
| Mixed race | 7.69% | 2.44% | 3.06% |
| Other race | 0.00% | 1.13% | 4.75% |
Here are the best places to live in Missouri
These are the largest cities in Missouri
See the best places to live in De Witt
These are the 10 cheapest cities in Missouri