| Index | Depew | New York | National |
| Average Test Scores | 59% | 56% | 48% |
| Student/Teacher ratio | n/a | n/a | 16:1 |
| Total public schools | 4 | 4,060 | 79,221 |
| Total private schools | 3 | 1,092 | 24,874 |
| Total post-secondary schools | n/a | 483 | 7,963 |
| Index | Depew | New York | National |
| Completed 8th grade | 89.2% | 83.5% | 84.3% |
| Completed high school | 88.5% | 82.1% | 83.0% |
| Completed some college | 51.6% | 59.5% | 59.4% |
| Completed associate degree | 31.8% | 43.4% | 38.5% |
| Completed bachelors | 20.1% | 34.7% | 30.3% |
| Completed masters | 5.9% | 15.1% | 11.5% |
| Completed professional degree | 0.6% | 4.2% | 3.3% |
| Completed doctorate | 0.1% | 1.5% | 1.3% |
There are a total of 4 public schools, 3 private schools and n/a post-secondary schools in Depew. Using the proficiency score averages, the average test scores for Depew, NY schools is 59%. The average student to teacher ratio is n/a. In Depew, NY, an average of 89.2% of students have completed 8th grade and an average of 88.5% have completed high school.
| City | Population | Avg. Test Scores | National Avg. |
| Clarence, NY | 2,238 | 83% | 72.6% |
| Williamsville, NY | 5,194 | 74% | 54.5% |
| East Aurora, NY | 6,172 | 73% | 51.0% |
| Akron, NY | 2,860 | 70% | 45.8% |
| Clarence Center, NY | 3,211 | 70% | 44.8% |
| Depew, NY | 15,069 | 59% | 22.9% |
| City | Population | Avg. Test Scores | National Avg. |
| St. Augustine, FL | 15,065 | 55% | 14.3% |
| Hayden, ID | 15,049 | 37% | 22.9% |
| Newport, KY | 15,045 | 37% | 23.6% |
| Greenwood Village, CO | 15,100 | 67% | 39.0% |
| Stone Ridge, VA | 15,034 | 88% | 83.3% |
| Depew, NY | 15,069 | 59% | 22.9% |
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