| Month | Temp. (min) | Temp. (max) | Temp. (avg) | Precipitation |
| January | 26°F | 41°F | 33°F | 9.0" |
| February | 25°F | 43°F | 33°F | 4.8" |
| March | 36°F | 60°F | 47°F | 3.9" |
| April | 44°F | 68°F | 55°F | 4.3" |
| May | 56°F | 80°F | 67°F | 4.3" |
| June | 65°F | 87°F | 76°F | 5.8" |
| July | 66°F | 89°F | 77°F | 3.9" |
| August | 69°F | 91°F | 79°F | 4.6" |
| September | 60°F | 85°F | 71°F | 4.9" |
| October | 48°F | 71°F | 59°F | 3.7" |
| November | 36°F | 58°F | 46°F | 7.6" |
| December | 25°F | 40°F | 32°F | 2.5" |
| Index | Elsberry | Missouri | National |
| Air quality index | 54 | 97 | 42 |
| Pollution index | 2,458,180 | 1,630,255 | 2,726,193 |
| Measurement | Total |
| Days measured | 365 |
| Days with good air quality | 134 |
| Days with moderate air quality | 221 |
| Days w/ poor A.Q. for sensitive groups | 8 |
| Days with unhealthy air quality | 2 |
| Pollutant | Total |
| Arsenic | 0.002% |
| Benzene | 0.020% |
| Carbon Tetrachloride | 0.001% |
| Lead | 0.120% |
| Mercury | 0.330% |
| City | Population | Air Quality Index | National Avg. |
| Eolia, MO | 305 | 41 | 18.0% |
| Whiteside, MO | 85 | 41 | 18.0% |
| Paynesville, MO | 28 | 41 | 18.0% |
| Clarksville, MO | 508 | 41 | 18.0% |
| Kampsville, IL | 321 | 54 | 8.0% |
| Elsberry, MO | 2,024 | 54 | 8.0% |
| City | Population | Air Quality Index | National Avg. |
| Starland County, AB | 2,024 | n/a | |
| Pahala, HI | 2,023 | 16 | 68.0% |
| Prairie Grove, IL | 2,023 | 39 | 22.0% |
| Montrose, MI | 2,023 | 38 | 24.0% |
| Mount Sterling, OH | 2,023 | 38 | 24.0% |
| Elsberry, MO | 2,024 | 54 | 8.0% |
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