| Statistic | Guion | Arkansas | National |
| Population | 91 | 3,017,825 | 328,239,523 |
| Population density (sq mi) | 163 | 58 | 91 |
| Median age | 35.2 | 37.7 | 37.7 |
| Male/Female ratio | 1.0:1 | 1.0:1 | 1.0:1 |
| Married (15yrs & older) | 33% | 58% | 55% |
| Families w/ Kids under 18 | 13% | 42% | 43% |
| Speak English | 98% | 93% | 79% |
| Speak Spanish | 0% | 5% | 13% |
| Race | Guion | Arkansas | National |
| White | 84.62% | 77.72% | 73.35% |
| Black | 0.00% | 15.52% | 12.63% |
| Asian | 0.00% | 1.40% | 5.22% |
| American Indian | 0.00% | 0.63% | 0.82% |
| Native Hawaiian | 0.00% | 0.23% | 0.18% |
| Mixed race | 15.38% | 2.23% | 3.06% |
| Other race | 0.00% | 2.28% | 4.75% |
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