| Month | Temp. (min) | Temp. (max) | Temp. (avg) | Precipitation |
| January | 28°F | 53°F | 39°F | 1.1" |
| February | 32°F | 56°F | 42°F | 2.7" |
| March | 43°F | 68°F | 54°F | 3.0" |
| April | 51°F | 76°F | 62°F | 5.2" |
| May | 59°F | 82°F | 69°F | 4.8" |
| June | 70°F | 92°F | 80°F | 5.4" |
| July | 73°F | 96°F | 84°F | 5.0" |
| August | 72°F | 95°F | 82°F | 3.9" |
| September | 63°F | 87°F | 74°F | 3.2" |
| October | 52°F | 77°F | 63°F | 3.2" |
| November | 41°F | 65°F | 52°F | 2.6" |
| December | 31°F | 52°F | 40°F | 1.4" |
| Index | Guthrie | Oklahoma | National |
| Air quality index | 48 | 55 | 42 |
| Pollution index | 395,464 | 1,271,533 | 2,726,193 |
| Measurement | Total |
| Days measured | 365 |
| Days with good air quality | 204 |
| Days with moderate air quality | 159 |
| Days w/ poor A.Q. for sensitive groups | 2 |
| Days with unhealthy air quality | 0 |
| Pollutant | Total |
| Arsenic | 0.000% |
| Benzene | 0.010% |
| Carbon Tetrachloride | 0.001% |
| Lead | 0.000% |
| Mercury | 0.000% |
| City | Population | Air Quality Index | National Avg. |
| Cedar Valley, OK | 470 | 48 | 4.0% |
| Langston, OK | 1,432 | 48 | 4.0% |
| Mulhall, OK | 240 | 48 | 4.0% |
| Cimarron City, OK | 189 | 48 | 4.0% |
| Arcadia, OK | 135 | 48 | 4.0% |
| Guthrie, OK | 11,296 | 48 | 4.0% |
| City | Population | Air Quality Index | National Avg. |
| Berkley, CO | 11,299 | 58 | 16.0% |
| Pasadena Hills, FL | 11,301 | 36 | 28.0% |
| Newport East, RI | 11,289 | 44 | 12.0% |
| Mapleton, ON | 11,305 | n/a | |
| Guttenberg, NJ | 11,284 | 51 | 2.0% |
| Guthrie, OK | 11,296 | 48 | 4.0% |
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