| Index | Karnes City | Texas | National |
| Average Test Scores | 43% | 47% | 48% |
| Student/Teacher ratio | 12:1 | 14:1 | 16:1 |
| Total public schools | 5 | 7,418 | 79,221 |
| Total private schools | n/a | 1,267 | 24,874 |
| Total post-secondary schools | n/a | 463 | 7,963 |
| Index | Karnes City | Texas | National |
| Completed 8th grade | 73.7% | 79.3% | 84.3% |
| Completed high school | 68.4% | 77.8% | 83.0% |
| Completed some college | 37.4% | 57.3% | 59.4% |
| Completed associate degree | 18.8% | 34.9% | 38.5% |
| Completed bachelors | 14.0% | 28.1% | 30.3% |
| Completed masters | 3.5% | 9.6% | 11.5% |
| Completed professional degree | 1.0% | 2.6% | 3.3% |
| Completed doctorate | 0.2% | 1.1% | 1.3% |
There are a total of 5 public schools, n/a private schools and n/a post-secondary schools in Karnes City. Using the proficiency score averages, the average test scores for Karnes City, TX schools is 43%. The average student to teacher ratio is 12:1. In Karnes City, TX, an average of 73.7% of students have completed 8th grade and an average of 68.4% have completed high school.
| City | Population | Avg. Test Scores | National Avg. |
| Falls City, TX | 1,001 | 80% | 65.6% |
| Poth, TX | 1,805 | 68% | 42.4% |
| Kenedy, TX | 3,394 | 39% | 19.4% |
| Runge, TX | 1,192 | 32% | 32.8% |
| Karnes City, TX | 3,398 | 43% | 11.5% |
| City | Population | Avg. Test Scores | National Avg. |
| Frontenac, KS | 3,398 | 35% | 26.4% |
| Jena, LA | 3,400 | 80% | 67.4% |
| Haworth, NJ | 3,400 | 81% | 67.7% |
| Newcastle, WY | 3,395 | 55% | 13.5% |
| Kenedy, TX | 3,394 | 39% | 19.4% |
| Karnes City, TX | 3,398 | 43% | 11.5% |
Here are the best places to live in Texas
These are the 10 cheapest cities in Texas
These are the largest cities in Texas
See the best places to live in Karnes City