| Month | Temp. (min) | Temp. (max) | Temp. (avg) | Precipitation |
| January | 21°F | 44°F | 31°F | 2.0" |
| February | 23°F | 47°F | 33°F | 2.1" |
| March | 35°F | 61°F | 46°F | 3.0" |
| April | 44°F | 71°F | 57°F | 5.7" |
| May | 53°F | 78°F | 65°F | 4.3" |
| June | 63°F | 87°F | 75°F | 4.8" |
| July | 67°F | 90°F | 78°F | 5.1" |
| August | 65°F | 89°F | 76°F | 3.9" |
| September | 57°F | 82°F | 69°F | 4.8" |
| October | 45°F | 71°F | 57°F | 3.9" |
| November | 35°F | 59°F | 46°F | 2.4" |
| December | 25°F | 45°F | 34°F | 2.7" |
| Index | Lupus | Missouri | National |
| Air quality index | 38 | 97 | 42 |
| Pollution index | 345,382 | 1,630,255 | 2,726,193 |
| Measurement | Total |
| Days measured | 245 |
| Days with good air quality | 239 |
| Days with moderate air quality | 6 |
| Days w/ poor A.Q. for sensitive groups | 0 |
| Days with unhealthy air quality | 0 |
| Pollutant | Total |
| Arsenic | 0.001% |
| Benzene | 0.010% |
| Carbon Tetrachloride | 0.001% |
| Lead | 0.000% |
| Mercury | 0.000% |
| City | Population | Air Quality Index | National Avg. |
| Huntsdale, MO | 21 | 38 | 24.0% |
| Prairie Home, MO | 243 | 38 | 24.0% |
| Windsor Place, MO | 390 | 38 | 24.0% |
| Ashland, MO | 3,956 | 38 | 24.0% |
| Jamestown, MO | 382 | 38 | 24.0% |
| Lupus, MO | 22 | 38 | 24.0% |
| City | Population | Air Quality Index | National Avg. |
| Dot Lake Village, AK | 22 | 38 | 24.0% |
| Coppock, IA | 22 | 35 | 30.0% |
| Pioneer, IA | 22 | 37 | 26.0% |
| Byers, KS | 22 | 15 | 70.0% |
| Irwin, MO | 22 | 37 | 26.0% |
| Lupus, MO | 22 | 38 | 24.0% |
Here are the best places to live in Missouri
See the best places to live in Lupus
These are the largest cities in Missouri
These are the 10 cheapest cities in Missouri