| Index | Matlacha Isles-Matlacha Shores | Florida | National |
| Average Test Scores | n/a | 55% | 48% |
| Student/Teacher ratio | n/a | 17:1 | 16:1 |
| Total public schools | n/a | 3,388 | 79,221 |
| Total private schools | n/a | 1,640 | 24,874 |
| Total post-secondary schools | n/a | 466 | 7,963 |
| Index | Matlacha Isles-Matlacha Shores | Florida | National |
| Completed 8th grade | 78.7% | 84.0% | 84.3% |
| Completed high school | 78.7% | 83.0% | 83.0% |
| Completed some college | 50.8% | 58.0% | 59.4% |
| Completed associate degree | 48.0% | 37.4% | 38.5% |
| Completed bachelors | 44.1% | 27.9% | 30.3% |
| Completed masters | 15.0% | 10.0% | 11.5% |
| Completed professional degree | 9.1% | 3.1% | 3.3% |
| Completed doctorate | 9.1% | 1.1% | 1.3% |
There are a total of n/a public schools, n/a private schools and n/a post-secondary schools in Matlacha Isles-Matlacha Shores. Using the proficiency score averages, the average test scores for Matlacha Isles-Matlacha Shores, FL schools is n/a. The average student to teacher ratio is n/a. In Matlacha Isles-Matlacha Shores, FL, an average of 78.7% of students have completed 8th grade and an average of 78.7% have completed high school.
| City | Population | Avg. Test Scores | National Avg. |
| Cypress Lake, FL | 12,766 | 91% | 89.6% |
| Sanibel, FL | 7,378 | 90% | 86.5% |
| Bokeelia, FL | 1,536 | 72% | 50.0% |
| Fort Myers Beach, FL | 7,102 | 65% | 35.4% |
| Cape Coral, FL | 189,633 | 61% | 28.0% |
| Matlacha Isles-Matlacha Shores, FL | 339 | n/a |
| City | Population | Avg. Test Scores | National Avg. |
| Maywood, NE | 339 | 58% | 19.8% |
| Lacona, IA | 339 | 62% | 29.2% |
| Bunceton, MO | 339 | 43% | 11.5% |
| Summit, SD | 339 | 47% | 1.6% |
| McIntosh, FL | 339 | 40% | 16.7% |
| Matlacha Isles-Matlacha Shores, FL | 339 | n/a |
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