| Index | Matlacha Isles-Matlacha Shores | Florida | National |
| Median home price | $338,700 | $166,800 | $184,700 |
| Median rent asked | $0 | $1,032 | $949 |
| Avg. people per household | 3.1 | 2.6 | 2.6 |
| Owner occupied households | 60.5% | 64.8% | 63.6% |
| Renter occupied households | 39.5% | 35.2% | 36.4% |
| Population | Home Price | National Avg. | |
| Page Park, FL | 621 | $0 | 100% |
| Palmona Park, FL | 754 | $0 | 100% |
| Suncoast Estates, FL | 4,759 | $70,400 | 62% |
| North Fort Myers, FL | 42,315 | $98,500 | 47% |
| Tice, FL | 5,379 | $109,600 | 41% |
| Matlacha Isles-Matlacha Shores, FL | 339 | $338,700 | 83% |
| Population | Home Price | National Avg. | |
| Mildred, TX | 339 | $79,300 | 57% |
| Summit, SD | 339 | $66,700 | 64% |
| Mitchellville, AR | 339 | $47,500 | 74% |
| Pleasant Grove, MD | 339 | $94,300 | 49% |
| Universal, IN | 339 | $55,900 | 70% |
| Matlacha Isles-Matlacha Shores, FL | 339 | $338,700 | 83% |
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