| Index | Mayo | South Carolina | National |
| Average Test Scores | 60% | 47% | 48% |
| Student/Teacher ratio | 18:1 | 16:1 | 16:1 |
| Total public schools | 1 | 932 | 79,221 |
| Total private schools | n/a | 369 | 24,874 |
| Total post-secondary schools | n/a | 96 | 7,963 |
| Index | Mayo | South Carolina | National |
| Completed 8th grade | 70.6% | 83.0% | 84.3% |
| Completed high school | 70.6% | 81.6% | 83.0% |
| Completed some college | 41.8% | 56.6% | 59.4% |
| Completed associate degree | 21.4% | 35.6% | 38.5% |
| Completed bachelors | 13.7% | 26.5% | 30.3% |
| Completed masters | 0.0% | 9.6% | 11.5% |
| Completed professional degree | 0.0% | 2.5% | 3.3% |
| Completed doctorate | 0.0% | 1.1% | 1.3% |
There are a total of 1 public schools, n/a private schools and n/a post-secondary schools in Mayo. Using the proficiency score averages, the average test scores for Mayo, SC schools is 60%. The average student to teacher ratio is 18:1. In Mayo, SC, an average of 70.6% of students have completed 8th grade and an average of 70.6% have completed high school.
| City | Population | Avg. Test Scores | National Avg. |
| Mooresboro, NC | 220 | 73% | 51.0% |
| Chesnee, SC | 597 | 60% | 25.2% |
| Inman, SC | 3,665 | 57% | 19.2% |
| Boiling Springs, SC | 9,953 | 56% | 17.4% |
| Cliffside, NC | 707 | 52% | 8.3% |
| Mayo, SC | 1,770 | 60% | 24.0% |
| City | Population | Avg. Test Scores | National Avg. |
| Fort Deposit, AL | 1,770 | 21% | 56.8% |
| Stamps, AR | 1,770 | 25% | 49.0% |
| Brodheadsville, PA | 1,770 | 60% | 25.5% |
| Columbia City, OR | 1,770 | 35% | 28.1% |
| Rogue River, OR | 1,770 | 33% | 32.3% |
| Mayo, SC | 1,770 | 60% | 24.0% |
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