| Month | Temp. (min) | Temp. (max) | Temp. (avg) | Precipitation |
| January | 28°F | 50°F | 38°F | 6.9" |
| February | 30°F | 54°F | 41°F | 3.8" |
| March | 37°F | 63°F | 49°F | 4.7" |
| April | 46°F | 73°F | 59°F | 6.5" |
| May | 54°F | 79°F | 66°F | 6.7" |
| June | 62°F | 87°F | 74°F | 8.2" |
| July | 66°F | 89°F | 76°F | 5.4" |
| August | 65°F | 87°F | 75°F | 5.4" |
| September | 58°F | 81°F | 68°F | 7.7" |
| October | 46°F | 72°F | 57°F | 6.1" |
| November | 36°F | 62°F | 47°F | 8.0" |
| December | 32°F | 54°F | 42°F | 6.4" |
| Index | Mayodan | North Carolina | National |
| Air quality index | 43 | 35 | 42 |
| Pollution index | 533,491 | 2,789,538 | 2,726,193 |
| Measurement | Total |
| Days measured | 365 |
| Days with good air quality | 291 |
| Days with moderate air quality | 74 |
| Days w/ poor A.Q. for sensitive groups | 0 |
| Days with unhealthy air quality | 0 |
| Pollutant | Total |
| Arsenic | 0.020% |
| Benzene | 0.003% |
| Carbon Tetrachloride | 0.001% |
| Lead | 0.020% |
| Mercury | 0.000% |
| City | Population | Air Quality Index | National Avg. |
| Stoneville, NC | 1,244 | 43 | 14.0% |
| Stokesdale, NC | 5,451 | 43 | 14.0% |
| Madison, NC | 2,178 | 43 | 14.0% |
| Ridgeway, VA | 1,165 | 43 | 14.0% |
| Wentworth, NC | 2,720 | 43 | 14.0% |
| Mayodan, NC | 2,352 | 43 | 14.0% |
| City | Population | Air Quality Index | National Avg. |
| Henry, IL | 2,352 | 41 | 18.0% |
| Woodbine, NJ | 2,352 | 40 | 20.0% |
| Croom, MD | 2,353 | 47 | 6.0% |
| Flora, MS | 2,353 | 44 | 12.0% |
| Collierville, CA | 2,354 | 45 | 10.0% |
| Mayodan, NC | 2,352 | 43 | 14.0% |
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