| Month | Temp. (min) | Temp. (max) | Temp. (avg) | Precipitation |
| January | 21°F | 38°F | 29°F | 4.4" |
| February | 21°F | 40°F | 30°F | 3.5" |
| March | 30°F | 52°F | 40°F | 5.0" |
| April | 40°F | 64°F | 51°F | 4.5" |
| May | 49°F | 72°F | 60°F | 6.0" |
| June | 57°F | 79°F | 68°F | 8.6" |
| July | 61°F | 82°F | 71°F | 9.8" |
| August | 59°F | 81°F | 69°F | 6.1" |
| September | 53°F | 76°F | 63°F | 6.0" |
| October | 42°F | 64°F | 52°F | 4.2" |
| November | 32°F | 54°F | 42°F | 3.7" |
| December | 26°F | 43°F | 34°F | 4.5" |
| Index | Millsboro | Pennsylvania | National |
| Air quality index | 36 | 45 | 42 |
| Pollution index | 889,808 | 4,584,805 | 2,726,193 |
| Measurement | Total |
| Days measured | 364 |
| Days with good air quality | 337 |
| Days with moderate air quality | 27 |
| Days w/ poor A.Q. for sensitive groups | 0 |
| Days with unhealthy air quality | 0 |
| Pollutant | Total |
| Arsenic | 0.001% |
| Benzene | 0.020% |
| Carbon Tetrachloride | 0.002% |
| Lead | 0.030% |
| Mercury | 0.030% |
| City | Population | Air Quality Index | National Avg. |
| Mather, PA | 495 | 36 | 28.0% |
| Masontown, PA | 3,314 | 36 | 28.0% |
| Greensboro, PA | 387 | 36 | 28.0% |
| Centerville borough (Crawford County), PA | 177 | 36 | 28.0% |
| Fredericktown, PA | 200 | 36 | 28.0% |
| Millsboro, PA | 503 | 36 | 28.0% |
| City | Population | Air Quality Index | National Avg. |
| Tehama, CA | 503 | 41 | 18.0% |
| Spring Lake, FL | 503 | 30 | 40.0% |
| Waco, GA | 503 | 44 | 12.0% |
| New Albin, IA | 503 | 35 | 30.0% |
| Scammon, KS | 503 | 37 | 26.0% |
| Millsboro, PA | 503 | 36 | 28.0% |
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