| Index | New Madrid | Missouri | National |
| Average Test Scores | 37% | 44% | 48% |
| Student/Teacher ratio | 13:1 | 14:1 | 16:1 |
| Total public schools | 5 | 1,899 | 79,221 |
| Total private schools | 1 | 531 | 24,874 |
| Total post-secondary schools | n/a | 213 | 7,963 |
| Index | New Madrid | Missouri | National |
| Completed 8th grade | 73.8% | 86.0% | 84.3% |
| Completed high school | 71.4% | 84.2% | 83.0% |
| Completed some college | 44.9% | 57.7% | 59.4% |
| Completed associate degree | 17.3% | 35.2% | 38.5% |
| Completed bachelors | 11.7% | 27.6% | 30.3% |
| Completed masters | 6.6% | 10.4% | 11.5% |
| Completed professional degree | 0.0% | 2.8% | 3.3% |
| Completed doctorate | 0.0% | 1.2% | 1.3% |
There are a total of 5 public schools, 1 private schools and n/a post-secondary schools in New Madrid. Using the proficiency score averages, the average test scores for New Madrid, MO schools is 37%. The average student to teacher ratio is 13:1. In New Madrid, MO, an average of 73.8% of students have completed 8th grade and an average of 71.4% have completed high school.
| City | Population | Avg. Test Scores | National Avg. |
| Matthews, MO | 635 | 72% | 50.0% |
| Portageville, MO | 2,959 | 42% | 12.2% |
| Risco, MO | 257 | 41% | 14.6% |
| East Prairie, MO | 2,980 | 34% | 28.8% |
| Lilbourn, MO | 1,044 | 25% | 49.0% |
| New Madrid, MO | 2,863 | 37% | 22.9% |
| City | Population | Avg. Test Scores | National Avg. |
| Decherd, TN | 2,862 | 17% | 64.6% |
| Ithaca, MI | 2,864 | 47% | 1.6% |
| Cold Spring Harbor, NY | 2,864 | 87% | 81.3% |
| Monterey, TN | 2,865 | 30% | 37.5% |
| Coalfield, TN | 2,861 | 21% | 56.3% |
| New Madrid, MO | 2,863 | 37% | 22.9% |
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