| Index | Picayune | Mississippi | National |
| Average Test Scores | 44% | 40% | 48% |
| Student/Teacher ratio | 14:1 | 16:1 | 16:1 |
| Total public schools | 9 | 893 | 79,221 |
| Total private schools | 4 | 206 | 24,874 |
| Total post-secondary schools | n/a | 68 | 7,963 |
| Index | Picayune | Mississippi | National |
| Completed 8th grade | 78.5% | 78.6% | 84.3% |
| Completed high school | 77.2% | 76.7% | 83.0% |
| Completed some college | 57.9% | 52.5% | 59.4% |
| Completed associate degree | 26.2% | 29.8% | 38.5% |
| Completed bachelors | 16.5% | 21.0% | 30.3% |
| Completed masters | 3.7% | 7.9% | 11.5% |
| Completed professional degree | 0.4% | 2.2% | 3.3% |
| Completed doctorate | 0.0% | 0.9% | 1.3% |
There are a total of 9 public schools, 4 private schools and n/a post-secondary schools in Picayune. Using the proficiency score averages, the average test scores for Picayune, MS schools is 44%. The average student to teacher ratio is 14:1. In Picayune, MS, an average of 78.5% of students have completed 8th grade and an average of 77.2% have completed high school.
| City | Population | Avg. Test Scores | National Avg. |
| Lacombe, LA | 7,294 | 76% | 57.8% |
| Pearl River, LA | 2,618 | 72% | 50.3% |
| Kiln, MS | 2,462 | 59% | 23.2% |
| Picayune, MS | 11,016 | 44% | 8.2% |
| City | Population | Avg. Test Scores | National Avg. |
| New Baltimore, VA | 11,017 | 86% | 78.1% |
| Middle Island, NY | 11,030 | 59% | 23.7% |
| Ontario, OR | 11,031 | 36% | 24.3% |
| Satellite Beach, FL | 11,000 | 76% | 58.5% |
| Bolivar, MO | 11,000 | 50% | 3.8% |
| Picayune, MS | 11,016 | 44% | 8.2% |
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