| Month | Temp. (min) | Temp. (max) | Temp. (avg) | Precipitation |
| January | 36°F | 61°F | 47°F | 5.3" |
| February | 38°F | 64°F | 50°F | 5.9" |
| March | 45°F | 73°F | 58°F | 6.4" |
| April | 53°F | 80°F | 66°F | 5.8" |
| May | 60°F | 85°F | 72°F | 4.5" |
| June | 69°F | 92°F | 80°F | 4.0" |
| July | 71°F | 94°F | 81°F | 5.2" |
| August | 71°F | 94°F | 81°F | 4.9" |
| September | 65°F | 90°F | 76°F | 3.8" |
| October | 52°F | 81°F | 66°F | 3.3" |
| November | 43°F | 71°F | 55°F | 4.2" |
| December | 39°F | 63°F | 50°F | 6.0" |
| Index | Pickens | Mississippi | National |
| Air quality index | 44 | 40 | 42 |
| Pollution index | 822,005 | 1,514,109 | 2,726,193 |
| Measurement | Total |
| Days measured | 365 |
| Days with good air quality | 256 |
| Days with moderate air quality | 109 |
| Days w/ poor A.Q. for sensitive groups | 0 |
| Days with unhealthy air quality | 0 |
| Pollutant | Total |
| Arsenic | 0.001% |
| Benzene | 0.030% |
| Carbon Tetrachloride | 0.001% |
| Lead | 0.030% |
| Mercury | 0.000% |
| City | Population | Air Quality Index | National Avg. |
| Sallis, MS | 238 | 33 | 34.0% |
| Durant, MS | 2,709 | 33 | 34.0% |
| Goodman, MS | 1,368 | 44 | 12.0% |
| Pickens, MS | 1,187 | 44 | 12.0% |
| City | Population | Air Quality Index | National Avg. |
| Fanning Springs, FL | 1,187 | 35 | 30.0% |
| New Sharon, IA | 1,187 | 39 | 22.0% |
| Glandorf, OH | 1,187 | 39 | 22.0% |
| Fairland, OK | 1,187 | 38 | 24.0% |
| Tower City, PA | 1,187 | 42 | 16.0% |
| Pickens, MS | 1,187 | 44 | 12.0% |
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