| Statistic | Port Deposit | Maryland | National |
| Population | 624 | 6,045,680 | 328,239,523 |
| Population density (sq mi) | 276 | 627 | 91 |
| Median age | 40.0 | 38.3 | 37.7 |
| Male/Female ratio | 1.2:1 | 0.9:1 | 1.0:1 |
| Married (15yrs & older) | 51% | 54% | 55% |
| Families w/ Kids under 18 | 34% | 44% | 43% |
| Speak English | 98% | 82% | 79% |
| Speak Spanish | 2% | 7% | 13% |
| Race | Port Deposit | Maryland | National |
| White | 78.53% | 57.19% | 73.35% |
| Black | 13.78% | 29.63% | 12.63% |
| Asian | 0.00% | 6.08% | 5.22% |
| American Indian | 0.00% | 0.27% | 0.82% |
| Native Hawaiian | 0.00% | 0.05% | 0.18% |
| Mixed race | 7.37% | 3.12% | 3.06% |
| Other race | 0.32% | 3.67% | 4.75% |
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