| Month | Temp. (min) | Temp. (max) | Temp. (avg) | Precipitation |
| January | 32°F | 49°F | 39°F | 7.7" |
| February | 33°F | 50°F | 40°F | 4.5" |
| March | 43°F | 63°F | 52°F | 7.4" |
| April | 52°F | 73°F | 62°F | 8.3" |
| May | 60°F | 81°F | 70°F | 8.4" |
| June | 69°F | 90°F | 79°F | 7.5" |
| July | 70°F | 90°F | 79°F | 6.1" |
| August | 70°F | 91°F | 79°F | 4.3" |
| September | 63°F | 84°F | 72°F | 5.8" |
| October | 50°F | 73°F | 60°F | 7.7" |
| November | 41°F | 61°F | 50°F | 7.0" |
| December | 35°F | 51°F | 42°F | 7.8" |
| Index | Portageville | Missouri | National |
| Air quality index | 26 | 97 | 42 |
| Pollution index | 2,322,230 | 1,630,255 | 2,726,193 |
| Measurement | Total |
| Days measured | 360 |
| Days with good air quality | 341 |
| Days with moderate air quality | 19 |
| Days w/ poor A.Q. for sensitive groups | 0 |
| Days with unhealthy air quality | 0 |
| Pollutant | Total |
| Arsenic | 0.230% |
| Benzene | 0.040% |
| Carbon Tetrachloride | 0.001% |
| Lead | 0.001% |
| Mercury | 0.120% |
| City | Population | Air Quality Index | National Avg. |
| Lilbourn, MO | 1,044 | 26 | 48.0% |
| North Lilbourn, MO | 187 | 26 | 48.0% |
| Clarkton, MO | 1,105 | 26 | 48.0% |
| Hayward, MO | 79 | 26 | 48.0% |
| Wardell, MO | 420 | 26 | 48.0% |
| Portageville, MO | 2,959 | 26 | 48.0% |
| City | Population | Air Quality Index | National Avg. |
| Escatawpa, MS | 2,958 | 32 | 36.0% |
| Bishop's Falls, NL | 2,958 | n/a | |
| Division No. 8, Subd. L, NL | 2,960 | n/a | |
| Winchester, CA | 2,957 | 89 | 78.0% |
| New Britain, PA | 2,957 | 51 | 2.0% |
| Portageville, MO | 2,959 | 26 | 48.0% |
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