| Index | Prairie Home | Missouri | National |
| Average Test Scores | 40% | 44% | 48% |
| Student/Teacher ratio | n/a | 14:1 | 16:1 |
| Total public schools | n/a | 1,899 | 79,221 |
| Total private schools | n/a | 531 | 24,874 |
| Total post-secondary schools | n/a | 213 | 7,963 |
| Index | Prairie Home | Missouri | National |
| Completed 8th grade | 85.3% | 86.0% | 84.3% |
| Completed high school | 84.0% | 84.2% | 83.0% |
| Completed some college | 56.4% | 57.7% | 59.4% |
| Completed associate degree | 23.3% | 35.2% | 38.5% |
| Completed bachelors | 18.4% | 27.6% | 30.3% |
| Completed masters | 13.5% | 10.4% | 11.5% |
| Completed professional degree | 2.5% | 2.8% | 3.3% |
| Completed doctorate | 2.5% | 1.2% | 1.3% |
There are a total of n/a public schools, n/a private schools and n/a post-secondary schools in Prairie Home. Using the proficiency score averages, the average test scores for Prairie Home, MO schools is 40%. The average student to teacher ratio is n/a. In Prairie Home, MO, an average of 85.3% of students have completed 8th grade and an average of 84.0% have completed high school.
| City | Population | Avg. Test Scores | National Avg. |
| Jamestown, MO | 382 | 51% | 6.3% |
| California, MO | 4,411 | 51% | 5.2% |
| New Franklin, MO | 1,016 | 47% | 2.1% |
| Clarksburg, MO | 280 | 45% | 6.3% |
| Columbia, MO | 122,659 | 43% | 9.6% |
| Prairie Home, MO | 243 | 40% | 16.7% |
| City | Population | Avg. Test Scores | National Avg. |
| Koyuk, AK | 243 | 10% | 79.2% |
| McNeal, AZ | 243 | 40% | 16.7% |
| Hornbrook, CA | 243 | 30% | 37.5% |
| Cashtown, PA | 244 | 63% | 31.3% |
| Brookville, KS | 242 | 20% | 59.4% |
| Prairie Home, MO | 243 | 40% | 16.7% |
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