| Month | Temp. (min) | Temp. (max) | Temp. (avg) | Precipitation |
| January | 28°F | 47°F | 36°F | 3.2" |
| February | 30°F | 49°F | 39°F | 3.4" |
| March | 40°F | 62°F | 50°F | 5.9" |
| April | 49°F | 72°F | 60°F | 7.0" |
| May | 58°F | 79°F | 68°F | 5.6" |
| June | 68°F | 89°F | 78°F | 3.1" |
| July | 70°F | 90°F | 79°F | 4.3" |
| August | 68°F | 89°F | 77°F | 3.5" |
| September | 60°F | 83°F | 70°F | 4.2" |
| October | 48°F | 73°F | 59°F | 4.1" |
| November | 38°F | 60°F | 48°F | 4.7" |
| December | 32°F | 49°F | 39°F | 5.2" |
| Index | Puxico | Missouri | National |
| Air quality index | 26 | 97 | 42 |
| Pollution index | 647,211 | 1,630,255 | 2,726,193 |
| Measurement | Total |
| Days measured | 360 |
| Days with good air quality | 341 |
| Days with moderate air quality | 19 |
| Days w/ poor A.Q. for sensitive groups | 0 |
| Days with unhealthy air quality | 0 |
| Pollutant | Total |
| Arsenic | 0.001% |
| Benzene | 0.010% |
| Carbon Tetrachloride | 0.001% |
| Lead | 0.001% |
| Mercury | 0.000% |
| City | Population | Air Quality Index | National Avg. |
| Bloomfield, MO | 2,404 | 26 | 48.0% |
| Dudley, MO | 168 | 26 | 48.0% |
| Fisk, MO | 562 | 26 | 48.0% |
| Poplar Bluff, MO | 16,979 | 26 | 48.0% |
| Dexter, MO | 7,867 | 26 | 48.0% |
| Puxico, MO | 1,133 | 26 | 48.0% |
| City | Population | Air Quality Index | National Avg. |
| Cottonwood, AL | 1,133 | 35 | 30.0% |
| Steele, AL | 1,133 | 43 | 14.0% |
| Wickes, AR | 1,133 | 39 | 22.0% |
| Fairmead, CA | 1,133 | 50 | = 100 |
| Lake Telemark, NJ | 1,133 | 34 | 32.0% |
| Puxico, MO | 1,133 | 26 | 48.0% |
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