| Statistic | Pico-Lowell | Santa Ana | California |
| Population | 10,654 | 332,610 | 39,512,223 |
| Population density (sq mi) | 21,339 | 12,149 | 256 |
| Median age | 34.2 | 32.6 | 36.0 |
| Male/Female ratio | 1.1:1 | 1.1:1 | 1.0:1 |
| Married (15yrs & older) | n/a | 48% | 52% |
| Families w/ Kids under 18 | 49% | 46% | 46% |
| Speak English | n/a | 21% | 56% |
| Speak Spanish | n/a | 67% | 29% |
| Race | Pico-Lowell | Santa Ana | California |
| White | 14.06% | 35.64% | 61.26% |
| Black | 0.01% | 1.02% | 5.85% |
| Asian | 1.42% | 12.09% | 13.85% |
| American Indian | 0.98% | 0.58% | 0.74% |
| Native Hawaiian | 0.02% | 0.23% | 0.39% |
| Mixed race | 6.00% | 5.70% | 4.62% |
| Other race | 77.51% | 44.73% | 13.28% |
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