| Index | St. Charles | Missouri | National |
| Average Test Scores | 55% | 44% | 48% |
| Student/Teacher ratio | 15:1 | 14:1 | 16:1 |
| Total public schools | 37 | 1,899 | 79,221 |
| Total private schools | 14 | 531 | 24,874 |
| Total post-secondary schools | 2 | 213 | 7,963 |
| Index | St. Charles | Missouri | National |
| Completed 8th grade | 90.1% | 86.0% | 84.3% |
| Completed high school | 88.3% | 84.2% | 83.0% |
| Completed some college | 67.1% | 57.7% | 59.4% |
| Completed associate degree | 44.4% | 35.2% | 38.5% |
| Completed bachelors | 35.1% | 27.6% | 30.3% |
| Completed masters | 12.8% | 10.4% | 11.5% |
| Completed professional degree | 1.9% | 2.8% | 3.3% |
| Completed doctorate | 0.9% | 1.2% | 1.3% |
There are a total of 37 public schools, 14 private schools and 2 post-secondary schools in St. Charles. Using the proficiency score averages, the average test scores for St. Charles, MO schools is 55%. The average student to teacher ratio is 15:1. In St. Charles, MO, an average of 90.1% of students have completed 8th grade and an average of 88.3% have completed high school.
| City | Population | Avg. Test Scores | National Avg. |
| Clayton, MO | 16,763 | 73% | 52.7% |
| Dardenne Prairie, MO | 13,385 | 73% | 51.0% |
| Lake St. Louis, MO | 16,357 | 71% | 48.4% |
| Brentwood, MO | 7,986 | 70% | 45.6% |
| Weldon Spring, MO | 5,536 | 70% | 45.5% |
| St. Charles, MO | 70,650 | 55% | 15.4% |
| City | Population | Avg. Test Scores | National Avg. |
| Wilmington, DE | 70,655 | 36% | 24.1% |
| North Richland Hills, TX | 70,585 | 54% | 13.3% |
| Canton, OH | 70,863 | 52% | 8.4% |
| Weston, FL | 70,965 | 82% | 70.9% |
| Woodbury, MN | 71,298 | 70% | 46.5% |
| St. Charles, MO | 70,650 | 55% | 15.4% |
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